Cyproterone acetate

• Catalog No.: C989100
• CAS Number: 427-51-0
• M. F.: C24H29ClO4
• M. W.: 416.93766
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,2S,3S,5R,11R,12S,15R,16S)-15-acetyl-9-chloro-2,16-dimethyl-6-oxopentacyclo[9.7.0.0^2,^8.0^3,^5.0^1^2,^1^6]octadeca-7,9-dien-15-yl acetate
• IUPAC Traditional name: cyproterone acetate
• Synonyms: (1β,2β)-17-(Acetyloxy)-6-chloro-1,2-dihydro-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione; SH 714; CPA; Cyproterone 17-O-Acetate; Cyproterone 17α-Acetate; Androcur; 1,2α-Methylene-6-chloro-pregna-4,6-diene-3,20-dione 17α-Acetate; 6-Chloro-17-hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione Acetate; Cyprostat; Cyproviron; NSC 81430

DATABASE IDS

• CAS Number: 427-51-0

PROPERTIES

• Apperance: White Solid
• Melting Point: 209-211°C
• Solubility: Chloroform
• Solubility: Ethyl Acetate
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

The free alcohol is an anti-androgen; the acetate is both an anti-androgen and a progestogen. Combined with estrogen it is used in the treatment of acne.

REFERENCES

• Moltz, L., et al.: Contraception, 21, 393 (1980)
• Hammerstein, J., et al.: J. Steroid Biochem., 29, 591 (1983)