Cyproterone-13C2,d8

• Catalog No.: C989093
• M. F.: C22H27ClO3
• M. W.: 376.88628968

SYNONYMS

• IUPAC name: (1S,2R,3S,5R,11R,12S,15R,16S)-15-[(1,2-^1^3C₂,^2H₃)acetyl]-9-chloro-15-hydroxy-2-(^2H₃)methyl-16-methyl(5,7-^2H₂)pentacyclo[9.7.0.0^2,^8.0^3,^5.0^1^2,^1^6]octadeca-7,9-dien-6-one
• IUPAC Traditional name: (1S,2R,3S,5R,11R,12S,15R,16S)-15-[(1,2-^1^3C₂,^2H₃)acetyl]-9-chloro-15-hydroxy-2-(^2H₃)methyl-16-methyl(5,7-^2H₂)pentacyclo[9.7.0.0^2,^8.0^3,^5.0^1^2,^1^6]octadeca-7,9-dien-6-one
• Synonyms: 6-Chloro-17-hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione-13C2,d8; 1,2α-Methylene-6-chloro-6-17α-hydroxyprogesterone-13C2,d8; 6-Chloro-6-dehydro-17α-hydroxy-1,2α-methyleneprogesterone-13C2,d8; (1β,2β)-6-Chloro-1,2-dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione-13C2,d8

DETAILS

Description (English)

Labelled Cyproterone (C989090). An antiandrogen, suppresses Testosterone and its metabolites. Derivatives of Cyproterone are administered to patients suffering from hypersexuality and to help facilitate the sexual transformation of male-to-female transsex

REFERENCES

• Gracia, T., et al.: Toxicol. App. Pharmacol., 225, 142 (2007)
• Ahlin, G., et al.: J. Med. Chem., 51, 5932 (2007)
• Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2007)
• Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2007)