Cyproterone

• Catalog No.: C989090
• CAS Number: 2098-66-0
• M. F.: C22H27ClO3
• M. W.: 374.90098

SYNONYMS

• IUPAC name: (1S,2S,3S,5R,11R,12S,15R,16S)-15-acetyl-9-chloro-15-hydroxy-2,16-dimethylpentacyclo[9.7.0.0^2,^8.0^3,^5.0^1^2,^1^6]octadeca-7,9-dien-6-one
• IUPAC Traditional name: cyproterone
• Synonyms: 6-Chloro-6-dehydro-17α-hydroxy-1,2α-methyleneprogesterone; 6-Chloro-17-hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione; 1,2α-Methylene-6-chloro-6-17α-hydroxyprogesterone; (1β,2β)-6-Chloro-1,2-dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione

DATABASE IDS

• CAS Number: 2098-66-0

PROPERTIES

• Apperance: White Solid
• Melting Point: 208-210°C
• Solubility: Chloroform
• Solubility: Methanol

DETAILS

Description (English)

An antiandrogen, suppresses Testosterone and its metabolites. Derivatives of Cyproterone are administered to patients suffering from hypersexuality and to help facilitate the sexual transformation of male-to-female transsexuals.

REFERENCES

• Gracia, T., et al.: Toxicol. App. Pharmacol., 225, 142 (2007)
• Ahlin, G., et al.: J. Med. Chem., 51, 5932 (2007)
• Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2007)
• Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2007)