Cyclothiazide

• Catalog No.: C988960
• CAS Number: 2259-96-3
• M. F.: C14H16ClN3O4S2
• M. W.: 389.87754

SYNONYMS

• IUPAC name: 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ^6,2,4-benzothiadiazine-7-sulfonamide
• IUPAC Traditional name: cyclothiazide
• Synonyms: Lilly 35483; Fluidil; Valmiran; Anhydron; 3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide; 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide; Aquirel; Doburil; MDi 193; Renazide

DATABASE IDS

• CAS Number: 2259-96-3

DETAILS

Description (English)

Diuretic; antihypertensive. A subunit-specific inhibitor of GABAC receptors.

REFERENCES

• Wentling, C.D., et al.: Anal. Profiles Drug Subs., 1, 65 (1972)
• Dingledine, R., et al.: Pharmacol. Rev., 51, 7 (1972)
• Qian, H., et al.: J. Neurobiol., 40, 67 (1972)
• Qian, H., et al.: Mol. Pharmacol., 67, 470 (1972)
• Hadley, S., et al.: J. Physiol., 581