Cyclosporin H

• Catalog No.: C988920
• CAS Number: 83602-39-5
• M. F.: C19H39NO2
• M. W.: 313.51846
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (7R,8R,10E)-6-(dimethylamino)-7-hydroxy-8-methyldodec-10-en-5-one; butane
• IUPAC Traditional name: (7R,8R,10E)-6-(dimethylamino)-7-hydroxy-8-methyldodec-10-en-5-one; butane
• Synonyms: Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]; Sandoz 37-839; Cyclosporine H; 5-(N-Methyl-D-valine)cyclosporin A

DATABASE IDS

• CAS Number: 83602-39-5

PROPERTIES

• Apperance: White Solid
• Melting Point: 148-151°C
• Solubility: Acetone
• Solubility: Chloroform
• Solubility: Ethanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

REFERENCES

• van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988)
• Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (1988)
• Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (1988)