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Cyclosporin H_Molecular_structure_CAS_83602-39-5)
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Cyclosporin H

Catalog No. C988920 Name Toronto Research Chemicals
CAS Number 83602-39-5 Website http://www.trc-canada.com
M. F. C19H39NO2 Telephone +1 (416) 665-9696
M. W. 313.51846 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 165307

SYNONYMS

IUPAC name
(7R,8R,10E)-6-(dimethylamino)-7-hydroxy-8-methyldodec-10-en-5-one; butane
IUPAC Traditional name
(7R,8R,10E)-6-(dimethylamino)-7-hydroxy-8-methyldodec-10-en-5-one; butane
Synonyms
Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]
Sandoz 37-839
Cyclosporine H
5-(N-Methyl-D-valine)cyclosporin A

DATABASE IDS

CAS Number 83602-39-5

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 148-151°C
Solubility Acetone
Solubility Chloroform
Solubility Ethanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

REFERENCES

  • van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988)
  • Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (1988)
  • Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (1988)