Cyclosporin AM 1

• Catalog No.: C988915
• CAS Number: 89270-28-0
• M. F.: C30H59N3O5
• M. W.: 541.80656
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (2S)-N-[(1S)-1-{[(7R,8R,10E)-7,12-dihydroxy-8-methyl-5-oxododec-10-en-6-yl](methyl)carbamoyl}-2-methylpropyl]-4-methyl-2-(methylamino)pentanamide; butane
• IUPAC Traditional name: (2S)-N-[(1S)-1-{[(7R,8R,10E)-7,12-dihydroxy-8-methyl-5-oxododec-10-en-6-yl](methyl)carbamoyl}-2-methylpropyl]-4-methyl-2-(methylamino)pentanamide; butane
• Synonyms: 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; OL 17; Cyclosporin Metabolite 17; M 17; Cyclosporin A Metabolite 17

DATABASE IDS

• CAS Number: 89270-28-0

PROPERTIES

• Apperance: White Solid
• Melting Point: 146-148°C
• Solubility: Chloroform
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A cyclosporine metabolite specifically inhibits growth of renal cells in culture.

REFERENCES

• Johnson, B., et al.: Drug Metab. Dispos., 34, 556 (1991)
• Westley, I.S., Drug Metab. Dispos., 36, 46 (2008).
• Schultz, J.C.; et al.: Biochem. Pharma., 42, 1403 (1991)