Cyclosporin A

• Catalog No.: C988900
• CAS Number: 59865-13-3
• M. F.: C29H55N3O4
• M. W.: 509.7647
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2S)-N-[(3S,13R,14R,16E)-12-(dimethylamino)-13-hydroxy-2,14-dimethyl-4,11-dioxooctadec-16-en-3-yl]-4-methyl-2-(methylamino)pentanamide
• IUPAC Traditional name: (2S)-N-[(3S,13R,14R,16E)-12-(dimethylamino)-13-hydroxy-2,14-dimethyl-4,11-dioxooctadec-16-en-3-yl]-4-methyl-2-(methylamino)pentanamide
• Synonyms: Optimmune; Cyclosporine; Ciclosporin; Restasis; Atopica; Sandimmun(e); Neoral

DATABASE IDS

• CAS Number: 59865-13-3

PROPERTIES

• Apperance: White Solid
• Melting Point: 148-151°C
• Solubility: Acetone
• Solubility: Chloroform
• Solubility: Ethanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

REFERENCES

• van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988)
• Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (1988)
• Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (1988)