Cyclosporin A-13C2,d4 Acetate

• Catalog No.: C988893
• M. F.: C34H67N3O5
• M. W.: 599.89818968
• Storage: Refrigerator, under inert atmosphere

SYNONYMS

• IUPAC name: bis(butane) (6R,8E)-4-[(2S)-N,3-dimethyl-2-[(2S)-4-methyl-2-(methylamino)pentanamido]butanamido]-6-methyl-3-oxo(9,10-^1^3C₂,9,10,10,10-^2H₄)dec-8-en-5-yl acetate
• IUPAC Traditional name: bis(butane) (6R,8E)-4-[(2S)-N,3-dimethyl-2-[(2S)-4-methyl-2-(methylamino)pentanamido]butanamido]-6-methyl-3-oxo(9,10-^1^3C₂,9,10,10,10-^2H₄)dec-8-en-5-yl acetate
• Synonyms: Ciclosporin-13C2,d4 Acetate; Optimmune-13C2,d4 Acetate; Cyclosporine-13C2,d4 Acetate; Sandimmun(e)-13C2,d4 Acetate; Atopica-13C2,d4 Acetate; Neoral-13C2,d4 Acetate; Restasis-13C2,d4 Acetate

PROPERTIES

• Apperance: White Foam
• Solubility: Acetone
• Solubility: Chloroform
• Solubility: Benzene
• Storage Condition: Refrigerator, under inert atmosphere

DETAILS

Description (English)

Labelled Cyclosporin A (C988901) derivative. An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

REFERENCES

• van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988)
• Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (1988)
• Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005)