(5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-6-(methylamino)-morphinan-3,14-diol

• Catalog No.: C988740
• CAS Number: 102869-99-8
• M. F.: C21H28N2O3
• M. W.: 356.45862
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (1S,5R,13R,14S,17S)-4-(cyclopropylmethyl)-14-(methylamino)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,17-diol
• IUPAC Traditional name: (1S,5R,13R,14S,17S)-4-(cyclopropylmethyl)-14-(methylamino)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,17-diol
• Synonyms: Des-N-(3-furanyl-2-propenamide) Nalfurafine

DATABASE IDS

• CAS Number: 102869-99-8

PROPERTIES

• Apperance: White Solid
• Solubility: Dimethyl Sulfoxide
• Solubility: Ethyl Acetate
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Opioid receptor antagonist. Used in the preparation of opioid κ-agonist TRK-820 and other related compounds.

REFERENCES

• Mohamed, M.S. et al.: J. Med. Chem. 29, 1551 (1986)
• Nagase, H. et al.: Chem. Pharm. Bull. 46, 366 (1998).