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8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE_Molecular_structure_CAS_102146-07-6)
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8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE

Catalog No. C988500 Name Toronto Research Chemicals
CAS Number 102146-07-6 Website http://www.trc-canada.com
M. F. C16H24N4O2 Telephone +1 (416) 665-9696
M. W. 304.38736 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 92978

SYNONYMS

IUPAC name
8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
IUPAC Traditional name
dipropylcyclopentylxanthine
Synonyms
DPCPX, PD 116,948
8-Cyclopentyl-3,9-dihydro-1,3-dipropyl-1H-purine-2,6-dione

DATABASE IDS

CAS Number 102146-07-6

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 191-194°C
Solubility DMSO (3.6 mg/ml)
Solubility Ethanol (4 mg/ml)
Solubility 0.1N Sodium Hydroxide (2 mg/ml)
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist.

REFERENCES

  • Gessi, S., et al.: Mol. Pharmacol., 67, 2137 (2005)
  • Minor, T.R., et al.: Behav. Neurosci., 122, 1236 (2005)
  • Gracia, E., et al.: J. Neurochem., 107, 161 (2005)
  • Gessi, S., et al.: Biochem. Pharmacol., 75, 562 (2005)