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Cyclizine Hydrochloride

Catalog No. C987805 Name Toronto Research Chemicals
CAS Number 303-25-3 Website http://www.trc-canada.com
M. F. C18H23ClN2 Telephone +1 (416) 665-9696
M. W. 302.84162 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 104179

SYNONYMS

IUPAC name
1-(diphenylmethyl)-4-methylpiperazine hydrochloride
IUPAC Traditional name
wellcome hydrochloride
Synonyms
N-Benzhydryl-N'-methylpiperazine Monohydrochloride
1-(Diphenylmethyl)-4-methylpiperazine Hydrochloride
Marezine Hydrochloride
Marzine

DATABASE IDS

CAS Number 303-25-3

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 291-293°C
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
Cyclizine is a piperazine derivative with anti-emetic activity that is useful in the prevention and treatment of nausea and vomiting associated with motion sickness. Antiemetic.

REFERENCES

  • Kuntzman, R., et al.: J. Pharmacol. Exp. Ther., 158, 332 (1967)
  • Walker, R., et al.: Eur. J. Pharm. Sci., 4, 301 (1967)
  • Dumasia, M., et al.: Xenobiotica, 32, 795 (1967)