(-)-Cyclazocine

• Catalog No.: C987740
• CAS Number: 7313-86-2
• M. F.: C18H25NO
• M. W.: 271.3972
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1R,9S)-10-(cyclopropylmethyl)-1,13-dimethyl-10-azatricyclo[7.3.1.0^2,^7]trideca-2(7),3,5-trien-4-ol
• IUPAC Traditional name: (1R,9S)-10-(cyclopropylmethyl)-1,13-dimethyl-10-azatricyclo[7.3.1.0^2,^7]trideca-2(7),3,5-trien-4-ol
• Synonyms: (-)-α-Cyclazocine; MCV 4512; l-Cyclazocine; (2R,6R,11R)-3-(Cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol; (-)-cis-Cyclazocine; NIH 10450

DATABASE IDS

• CAS Number: 7313-86-2

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 188-190°C
• Solubility: Chloroform
• Solubility: Ethanol
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Cyclazocine is a mu opioid antagonist and kappa opioid agonist; it blocks the dopamine response to nicotine.

REFERENCES

• Carr, L., et al.: Neurochem Res., 14, 511 (1989)
• Imperato, A., et al.: Eur. J. Pharmacol., 132, 337 (1989)
• Debonnel, G., et al.: Life Sci., 58, 721 (1989)
• Glick, S., et al.: Eur. J. Pharmacol., 357, 9 (1989)