(+)-Cyclazocine

• Catalog No.: C987735
• CAS Number: 7313-87-3
• M. F.: C18H25NO
• M. W.: 271.3972

SYNONYMS

• IUPAC name: (1S,9R)-10-(cyclopropylmethyl)-1,13-dimethyl-10-azatricyclo[7.3.1.0^2,^7]trideca-2(7),3,5-trien-4-ol
• IUPAC Traditional name: (1S,9R)-10-(cyclopropylmethyl)-1,13-dimethyl-10-azatricyclo[7.3.1.0^2,^7]trideca-2(7),3,5-trien-4-ol
• Synonyms: (+)-Cyclazocine; (+)-cis-Cyclazocine; MCV 4511; NIH 10449; (2S,6S,11S)-3-(Cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol; (+)-α-Cyclazocine; d-Cyclazocine

DATABASE IDS

• CAS Number: 7313-87-3

DETAILS

Description (English)

Cyclazocine is a mu opioid antagonist and kappa opioid agonist; it blocks the dopamine response to nicotine.

REFERENCES

• Remmers, A., et al.: J. Pharmacol. Exper. Ther., 288, 827 (1999)
• Wentland, M., et al.: Bioorg. Med. Chem. Lett., 11, 623 (1999)