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CYC-116

Catalog No. C987730 Name Toronto Research Chemicals
CAS Number 1059105-22-4 Website http://www.trc-canada.com
M. F. C18H20N6OS Telephone +1 (416) 665-9696
M. W. 368.456 Fax +1 (416) 665-4439
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SYNONYMS

IUPAC name
4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]-2,5-dihydropyrimidin-2-imine
IUPAC Traditional name
4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]-5H-pyrimidin-2-imine
Synonyms
5-[2,5-Dihydro-2-[[4-(4-morpholinyl)phenyl]imino]-4-pyrimidinyl]-4-methyl-2-thiazolamine

DATABASE IDS

CAS Number 1059105-22-4

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
An Aurora kinase inhibitor, used to treat patients with advanced solid tumors.

REFERENCES

  • Carlson, H., et al.: Mol. Pharmacol., 57, 213 (2000)
  • Hou, T., et al.: Curr. Pharm. Des., 10, 1011 (2000)
  • Verdonk, M., et al.: J. Med. Chem., 48, 6504 (2000)