CUR 61414

• Catalog No.: C835000
• CAS Number: 334998-36-6
• M. F.: C31H42N4O5
• M. W.: 550.68898
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: N-[(3S,5S)-1-(2H-1,3-benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
• IUPAC Traditional name: N-[(3S,5S)-1-(2H-1,3-benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
• Synonyms: N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide

DATABASE IDS

• CAS Number: 334998-36-6

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 35-40°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

CUR 61414 is a proline derivative as mediator of hedgehog signaling pathways for pharmaceutical and cosmetic uses. CUR 61414 is a Nucleoside analog. CUR 61414 is an antimetabolite antitumor combination Gemcitabine cancer treatment.

REFERENCES

• Van der Riet, P., et al.: Cancer Res., 54, 25 (1994)
• Hahn, H., et al.: Cell, 85, 841 (1994)
• Johnson, R., et al.: Science, 272, 1668 (1994)
• Ingham, P., et al.: Genes Dev., 15, 3059 (1994)