CP 55,940

• Catalog No.: C781410
• CAS Number: 83002-04-4
• M. F.: C25H26Cl3N7O
• M. W.: 546.87924

SYNONYMS

• IUPAC name: 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)piperidine-4-carboxamide hydrochloride
• IUPAC Traditional name: otenabant hydrochloride
• Synonyms: (1α,2β,5α)-(-)-5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol; (-)-CP 55940; 5-(1,1-Dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol; CP 55940; (-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol

DATABASE IDS

• CAS Number: 83002-04-4

DETAILS

Description (English)

CP 55,940 is a cannabinoid agonist which is considerably more potent than Δ9-THC in both behavioral tests and receptor binding assays. Displays high and roughly equal affinity for both central and peripheral cannabinoid receptors (Ki = 0.6 - 5.0 and 0.7 -

REFERENCES

• Wiley, et al.: Neuropharmacology, 34, 669 (1995)
• Griffin, et al.: J. Pharmacol. Exp. Ther., 285, 553 (1995)
• Thomas, et al.: J. Pharmacol. Exp. Ther., 285, 285 (1995)
• Ryberg, et al.: Br. J. Pharmacol., 152, 1092 (1995)