Cotinine N-α-D-Glucuronide

• Catalog No.: C725170
• M. F.: C16H20N2O7
• M. W.: 352.3392
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 1-[(2R,3S,4R,5R,6R)-6-carboxylato-3,4,5-trihydroxyoxan-2-yl]-3-[(2S)-1-methyl-5-oxopyrrolidin-2-yl]-1λ^5-pyridin-1-ylium
• IUPAC Traditional name: 1-[(2R,3S,4R,5R,6R)-6-carboxylato-3,4,5-trihydroxyoxan-2-yl]-3-[(2S)-1-methyl-5-oxopyrrolidin-2-yl]-1λ^5-pyridin-1-ylium
• Synonyms: 1-α-D-Glucopyranuronosyl-3-[(2S)-1-methyl-5-oxo-2-pyrrolidinyl]pyridinium Inner Salt

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 107-109°C
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A major metabolite of Nicotine in humans. Carcinogen.

REFERENCES

• Benowitz, N., et al.: Clin. Pharmacol. Ther., 56, 483 (1994)
• Nakajima, M., et al.: Drug Metab. Dispos., 24, 1212 (1994)
• Messina, E., et al.: J. Pharmacol. Exp. Ther., 282, 1608 (1994)
• Oscarson, M., et al.: Hum. Mutat., 20, 275 (1994)