Cotinine N-(4-Deoxy-4,5-didehydro)-β-D-glucuronide

• Catalog No.: C725160
• CAS Number: 146275-15-2
• M. F.: C16H18N2O6
• M. W.: 334.32392
• Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere

SYNONYMS

• IUPAC name: 1-[(2S,3S,4R)-6-carboxylato-3,4-dihydroxy-3,4-dihydro-2H-pyran-2-yl]-3-[(2S)-1-methyl-5-oxopyrrolidin-2-yl]-1λ^5-pyridin-1-ylium
• IUPAC Traditional name: 1-[(2S,3S,4R)-6-carboxylato-3,4-dihydroxy-3,4-dihydro-2H-pyran-2-yl]-3-[(2S)-1-methyl-5-oxopyrrolidin-2-yl]-1λ^5-pyridin-1-ylium
• Synonyms: N-(β-D-4-Deoxy-4,5-didehydroglucopyranosyl)uronate, Cotinium Inner Salt

DATABASE IDS

• CAS Number: 146275-15-2

PROPERTIES

• Apperance: Off-White Crystalline Solid
• Melting Point: 153-156°C (dec.)
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under inert atmosphere

DETAILS

Description (English)

A major metabolite of Nicotine in humans. Carcinogen.

REFERENCES

• Benowitz, N., et al.: Clin. Pharmacol. Ther., 56, 483 (1994)
• Nakajima, M., et al.: Drug Metab. Dispos., 24, 1212 (1994)
• Messina, E., et al.: J. Pharmacol. Exp. Ther., 282, 1608 (1994)
• Oscarson, M., et al.: Hum. Mutat., 20, 275 (1994)