Coptisine Chloride

• Catalog No.: C685500
• CAS Number: 6020-18-4
• M. F.: C19H14ClNO4
• M. W.: 355.77176
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 5,7,17,19-tetraoxa-13λ^5-azahexacyclo[11.11.0.0^2,^1^0.0^4,^8.0^1^5,^2^3.0^1^6,^2^0]tetracosa-1(13),2,4(8),9,14,16(20),21,23-octaen-13-ylium chloride
• IUPAC Traditional name: coptisine chloride
• Synonyms: 7,8,13,13a-Tetradehydro-2,3:9,10-bis(methylenedioxy)berbinium Chloride; 6,7-Dihydrobis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium Chloride; Coptisine Chloride

DATABASE IDS

• CAS Number: 6020-18-4

PROPERTIES

• Apperance: Orange Brown Solid
• Melting Point: >258°C (dec.)
• Solubility: DMSO (Sparingly)
• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

Coptisine is an alkaloid found in Chinese goldthread (Coptis chinensis). A bacterial collagenase inhibitor. Coptisine has been found to reversibly inhibit Monoamine oxidase A in mice, pointing to a potential role as a natural antidepressant.

REFERENCES

• Blaney, W., et al.: Physiol. Entomol., 12, 281 (1987)
• Sethi, M., et al.: J. Pharm. Sci., 72, 538 (1987)
• Yahara, S., et al.: Chem. Pharm. Bull., 33, 527 (1987)