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Combretastatin A4_Molecular_structure_CAS_117048-59-6)
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Combretastatin A4

Catalog No. C643000 Name Toronto Research Chemicals
CAS Number 117048-59-6 Website http://www.trc-canada.com
M. F. C18H20O5 Telephone +1 (416) 665-9696
M. W. 316.3484 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 164948

SYNONYMS

IUPAC name
2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol
IUPAC Traditional name
combretastatin A-4
Synonyms
CS-A4
(Z)-2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, 3,4,5-Trimethoxy-3’-hydroxy-4’-methoxy-(Z)-stilbene

DATABASE IDS

CAS Number 117048-59-6

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 114-116°C
Solubility Chloroform
Solubility Ethyl Acetate
Solubility Hexane
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-

REFERENCES

  • Hamel, E., and Lin, C.M.: Biochem. Pharmacol., 32, 3863 (1983)
  • Chaplin, D.J., et al.: Br. J. Cancer, 74, S86, (1996)