Clozapine N-Oxide

• Catalog No.: C587520
• CAS Number: 34233-69-7
• M. F.: C18H19ClN4O
• M. W.: 342.82266
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-{6-chloro-2,9-diazatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-10-yl}-1-methylpiperazin-1-ium-1-olate
• IUPAC Traditional name: 4-{6-chloro-2,9-diazatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-10-yl}-1-methylpiperazin-1-ium-1-olate
• Synonyms: 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine N-Oxide

DATABASE IDS

• CAS Number: 34233-69-7

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 255-260°C (dec.)
• Solubility: Acetone
• Solubility: Ether
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A 5-HT2 antagonist. A major metabolite of clozapine that can be monitored by HPLC. Possesses little or no activity towards serotonin receptors.

REFERENCES

• Lin, G., et al.: J. Pharm. Sci, 83, 1412 (1994, Roth, B.L., et al.: J. Pharmacol. Exp. Ther., 268, 1403 (1994)