Clotiazepam-13C,d3

• Catalog No.: C587412
• M. F.: C16H15ClN2OS
• M. W.: 319.81375484

SYNONYMS

• IUPAC name: 5-(2-chlorophenyl)-7-ethyl-1-(^1^3C,^2H₃)methyl-1H,2H,3H-thieno[2,3-e][1,4]diazepin-2-one
• IUPAC Traditional name: 5-(2-chlorophenyl)-7-ethyl-1-(^1^3C,^2H₃)methyl-3H-thieno[2,3-e][1,4]diazepin-2-one
• Synonyms: Veratran-13C,d3; Rizen-13C,d3; 1-(Methyl-13C,d3)-5-o-chlorophenyl-7-ethyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepin-2-one; 5-(o-Chlorophenyl)-7-ethyl-1,3-dihydro-1-(methyl-13C,d3)-2H-thieno[2,3-e]-1,4-diazepin-2-one; 5-(o-Chlorophenyl)-7-ethyl-1-(methyl-13C,d3)-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepin-2-one; Tienor-13C,d3; Trecalmo-13C,d3; Y 6047-13C,d3; Clozan-13C,d3; Rize-13C,d3

DETAILS

Description (English)

A labelled thienodiazepine derivative that possesses anxiolytic, skeletal muscle relaxant anticonvulsant, sedative properties as well as contributing to siginificant increase stage 2 NREM sleep. It binds to benzodiazepine site of the GABAA receptor where

REFERENCES

• Mandrioli, R. et al.: Curr.Drug Metab., 8, 827 (2008)
• Nakazawa, Y. et al.: Psychopharmacol., 44, 165 (2008)
• Yakushiji, T. et al.: Br. J. Pharmacol., 98, 735 (2008)