Clotiazepam

• Catalog No.: C587410
• CAS Number: 33671-46-4
• M. F.: C16H15ClN2OS
• M. W.: 318.8211

SYNONYMS

• IUPAC name: 5-(2-chlorophenyl)-7-ethyl-1-methyl-1H,2H,3H-thieno[2,3-e][1,4]diazepin-2-one
• IUPAC Traditional name: rize
• Synonyms: Clozan; Trecalmo; 5-(o-Chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-2H-thieno[2,3-e]-1,4-diazepin-2-one; Tienor; 1-Methyl-5-o-chlorophenyl-7-ethyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepin-2-one; 5-(o-Chlorophenyl)-7-ethyl-1-methyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepin-2-one; Clotiazepam; Rize; Rizen; Veratran; Y 6047

DATABASE IDS

• CAS Number: 33671-46-4

DETAILS

Description (English)

A thienodiazepine derivative that possesses anxiolytic, skeletal muscle relaxant anticonvulsant, sedative properties as well as contributing to siginificant increase stage 2 NREM sleep. It binds to benzodiazepine site of the GABAA receptor where it acts a

REFERENCES

• Mandrioli, R. et al.: Curr.Drug Metab., 8, 827 (2008)
• Nakazawa, Y. et al.: Psychopharmacol., 44, 165 (2008)
• Yakushiji, T. et al.: Br. J. Pharmacol., 98, 735 (2008)