CI 1020-d9

• Catalog No.: C432682
• M. F.: C28H26O9
• M. W.: 506.50064

SYNONYMS

• IUPAC name: 3-(2H-1,3-benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-{[3,4,5-tris(^2H₃)methoxyphenyl]methyl}-2,5-dihydrofuran-2-one
• IUPAC Traditional name: 3-(2H-1,3-benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-{[3,4,5-tris(^2H₃)methoxyphenyl]methyl}furan-2-one
• Synonyms: PD 156707-d9; 3-(1,3-Benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-[(3,4,5-(trimethoxy-d9)phenyl)methyl]-2(5H)-furanone

DETAILS

Description (English)

Labelled CI 1020 (C432680). A novel endothelin-A receptor antagonist, in hypoxic pulmonary hypertension.

REFERENCES

• Yanagisawa, M., et al.: Nature, 332, 411 (1988)
• Reynolds, E., et al.: J. Pharmacol. Exp. Ther., 273, 1410 (1988)
• Chen, S., et al.: J. Cardiovasc. Pharmacol., 29, 713 (1988)
• Haleen, S., et al.: Exp. Opin. Invest. Drugs, 6, 475 (1988)