(Z)-2-(4-Chlorophenyl)-5-(4-methoxybenzylidene)-5H-thiazol-4-one_Molecular_structure_CAS_1272519-89-7)

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(Z)-2-(4-Chlorophenyl)-5-(4-methoxybenzylidene)-5H-thiazol-4-one
Catalog No.	C427750	Name	Toronto Research Chemicals
CAS Number	1272519-89-7	Website	http://www.trc-canada.com
M. F.	C17H12ClNO2S	Telephone	+1 (416) 665-9696
M. W.	329.80068	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 164718

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SYNONYMS

IUPAC name

(5Z)-2-(4-chlorophenyl)-5-[(4-methoxyphenyl)methylidene]-4,5-dihydro-1,3-thiazol-4-one

IUPAC Traditional name

(5Z)-2-(4-chlorophenyl)-5-[(4-methoxyphenyl)methylidene]-1,3-thiazol-4-one

Synonyms

(5Z)-2-(4-chlorophenyl)-5-[(4-methoxyphenyl)methylene]-4(5H)-thiazolone

CAY10649

DATABASE IDS

CAS Number

1272519-89-7

PROPERTIES

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DETAILS

Description (English)

A novel class of potent direct 5-lipoxygenase (5-LO) inhibitors bearing a thiazolinone-scaffold. These disubstituted thiazolinones may possess potential for intervention with inflammatory and allergic diseases and certain cancer types.Anti-inflammatory ag

REFERENCES

Werz, O., et al.: Pharmacol. Ther., 112, 701 (2006)
Franke, L., et al.: J. Med. Chem., 50, 2640 (2006)
Hofmann, B., et al.: ChemMedChem., 3, 1535 (2006)
Menna, C., et al.: Curr. Pharm. Des., 16, 725 (2006)