4-epi-Chlortetracycline Hydrochloride

• Catalog No.: C426501
• CAS Number: 101342-45-4
• M. F.: C22H24Cl2N2O8
• M. W.: 515.34056
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (4R,4aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
• IUPAC Traditional name: (4R,4aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide hydrochloride
• Synonyms: (4R,4aS,5aS,6S,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrate; 4-Epichlortetracycline Hydrochloride

DATABASE IDS

• CAS Number: 101342-45-4

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: >180°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Solubility: Pyridine
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A Tetracycline derivative. It is a metalloprotease inhibitor, used in treating tissue destructive diseases and cancer.

REFERENCES

• Golub, et al.: J. Periodont. Res., 20, 12 (1985)
• Maragoudakis, et al.: Br. J. Pharmacol., 111, 894 (1985)