N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea_Molecular_structure_CAS_330796-24-2)

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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea
Catalog No.	C421960	Name	Toronto Research Chemicals
CAS Number	330796-24-2	Website	http://www.trc-canada.com
M. F.	C23H15ClF4N4O2	Telephone	+1 (416) 665-9696
M. W.	490.8374128	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 164683

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SYNONYMS

IUPAC name

1-[4-chloro-3-(trifluoromethyl)phenyl]-3-{[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]methyl}urea

IUPAC Traditional name

1-[4-chloro-3-(trifluoromethyl)phenyl]-3-{[3-(4-fluorophenyl)-4-oxoquinazolin-2-yl]methyl}urea

DATABASE IDS

CAS Number

330796-24-2

PROPERTIES

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DETAILS

Description (English)

A potent modulator of Hedgehog (Hh) protein function; a nanomolar Hh antagonist.

REFERENCES

Chiang, C., et al.: Nature, 383, 407 (1996)
Hahn, H., et al.: Cell, 85, 841 (1996)
Johnson, R.L., et al.: Science, 272, 1668 (1996)
St.-Jacques, B., et al.: Genes Dev., 13, 2072 (1996)