Home > Compound List > Product Information
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea_Molecular_structure_CAS_330796-24-2)
Click picture or here to close

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea

Catalog No. C421960 Name Toronto Research Chemicals
CAS Number 330796-24-2 Website http://www.trc-canada.com
M. F. C23H15ClF4N4O2 Telephone +1 (416) 665-9696
M. W. 490.8374128 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 164683

SYNONYMS

IUPAC name
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-{[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]methyl}urea
IUPAC Traditional name
1-[4-chloro-3-(trifluoromethyl)phenyl]-3-{[3-(4-fluorophenyl)-4-oxoquinazolin-2-yl]methyl}urea

DATABASE IDS

CAS Number 330796-24-2

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
A potent modulator of Hedgehog (Hh) protein function; a nanomolar Hh antagonist.

REFERENCES

  • Chiang, C., et al.: Nature, 383, 407 (1996)
  • Hahn, H., et al.: Cell, 85, 841 (1996)
  • Johnson, R.L., et al.: Science, 272, 1668 (1996)
  • St.-Jacques, B., et al.: Genes Dev., 13, 2072 (1996)