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5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxylic acid_Molecular_structure_CAS_162758-35-2)
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5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxylic acid

Catalog No. C377830 Name Toronto Research Chemicals
CAS Number 162758-35-2 Website http://www.trc-canada.com
M. F. C17H11Cl3N2O2 Telephone +1 (416) 665-9696
M. W. 381.64044 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 67878

SYNONYMS

IUPAC name
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid
IUPAC Traditional name
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxylic acid
Synonyms
5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic Acid
1-(2,4-Dichlorophenyl)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic Acid

DATABASE IDS

CAS Number 162758-35-2

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 214-217°C
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxylic Acid is used in the preparation of biarylpyrazole based derivatives as cannabinoid CB1 receptor antagonists. It is metabolite M9 of Rimonabant (R517800), an antiobesity agent.

REFERENCES

  • Kang, S.Y. et al.: Bioorg. Med. Chem. Lett., 18, 2385 (2008)
  • Fulp, A. et al.: Bioorg. Med. Chem. Lett., 21, 5711 (2008)
  • Bergstrom, M.A. et al.: Drug Metab. and Dispos., 39, 1823 (2008)