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2-Chloroethyl Methanethiosulfonate_Molecular_structure_CAS_13700-02-2)
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2-Chloroethyl Methanethiosulfonate

Catalog No. C366125 Name Toronto Research Chemicals
CAS Number 13700-02-2 Website http://www.trc-canada.com
M. F. C3H7ClO2S2 Telephone +1 (416) 665-9696
M. W. 174.66948 Fax +1 (416) 665-4439
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SYNONYMS

IUPAC name
1-chloro-2-(methanesulfonylsulfanyl)ethane
IUPAC Traditional name
1-chloro-2-(methanesulfonylsulfanyl)ethane
Synonyms
Methanesulfonothioic Acid S-(2-Chloroethyl) Ester
2-Chloro-ethanethiol Methanesulfonate

DATABASE IDS

CAS Number 13700-02-2

PROPERTIES

Certificate of Analysis Download
Apperance Colourless Oil
Solubility Dichloromethane
Solubility Ether
Solubility Ethyl Acetate
Solubility Methanol
MSDS Link Download

DETAILS

Description (English)
Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. Useful for mapping the pore-lining regions of the ryanodine receptor.

REFERENCES

  • Yang, N. et al.: Neuron, 16, 113 (1996)
  • Kuner, T. et al.: Neuron, 17, 343 (1996)
  • Holmgren, M. et al: Neuropharmacology, 35, 797 (1996) Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1996)
  • Ehrlich, B.E., et al.: J. Gen. Physiol.,