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5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde _Molecular_structure_CAS_231278-84-5)
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5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde

Catalog No. C366385 Name Toronto Research Chemicals
CAS Number 231278-84-5 Website http://www.trc-canada.com
M. F. C26H17ClFN3O3 Telephone +1 (416) 665-9696
M. W. 473.8828832 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 164244

SYNONYMS

IUPAC name
5-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)quinazolin-6-yl]furan-2-carbaldehyde
IUPAC Traditional name
5-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)quinazolin-6-yl]furan-2-carbaldehyde
Synonyms
[5-[4-[4-[(3-Fluorobenzyl)oxy]-3-chloroanilino]-6-quinazolinyl]-2-furancarboxaldehyde

DATABASE IDS

CAS Number 231278-84-5

PROPERTIES

Certificate of Analysis Download
Apperance Dark Brown Solid
Melting Point >181°C (dec.)
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
Lapatinib intermediate.

REFERENCES

  • Khanna, I., et al.: J. Med. Chem., 40, 1619 (1997)
  • Liebowitz, S., et al.: Biochem. Pharmacol., 38, 399 (1997)
  • Klapper, L., et al.: Adv. Cancer Res., 77, 25 (1997)
  • Tiseo, M., et al.: Curr. Med. Chem., 4, 139 (1997)
  • Wood, E., et al.: Cancer Res., 64, 66