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N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-iodoquinazolin-4-amine_Molecular_structure_CAS_231278-20-9)
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N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-iodoquinazolin-4-amine

Catalog No. C366310 Name Toronto Research Chemicals
CAS Number 231278-20-9 Website http://www.trc-canada.com
M. F. C21H14ClFIN3O Telephone +1 (416) 665-9696
M. W. 505.7112332 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 164238

SYNONYMS

IUPAC name
N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-iodoquinazolin-4-amine
IUPAC Traditional name
N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-iodoquinazolin-4-amine
Synonyms
6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline
N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine

DATABASE IDS

CAS Number 231278-20-9

PROPERTIES

Certificate of Analysis Download
Apperance Yellow Solid
Melting Point 222-224°C
Solubility Methanol (warm)
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Lapatinib intermediate.

REFERENCES

  • Khanna, I., et al.: J. Med. Chem., 40, 1619 (1997)
  • Klapper, L., et al.: Adv. Cancer Res., 77, 25 (1997)
  • Rusnak, D., et al.: Cancer Res., 61, 7196 (1997)
  • Brignola, P., et al.: J. Biol. Chem., 277, 1576 (1997)