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2-Chloro-1-(4-fluorobenzyl)benzimidazole_Molecular_structure_CAS_84946-20-3)
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2-Chloro-1-(4-fluorobenzyl)benzimidazole

Catalog No. C366290 Name Toronto Research Chemicals
CAS Number 84946-20-3 Website http://www.trc-canada.com
M. F. C14H10ClFN2 Telephone +1 (416) 665-9696
M. W. 260.6940032 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 98274

SYNONYMS

IUPAC name
2-chloro-1-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazole
IUPAC Traditional name
2-chloro-1-[(4-fluorophenyl)methyl]-1,3-benzodiazole
Synonyms
2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole

DATABASE IDS

CAS Number 84946-20-3

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 83-86°C
Solubility Chloroform
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
A novel aldose reductase (ALR2) inhibitor. It is used for preparation of disubstituted benzimidazole derivative as anti-allergic agent (Mizolastine).

REFERENCES

  • Masson, E., et al.: Drugs, 39, 190 ( 1990), Lindstad, R., et al.: Eur. J. Biochem., 221, 847 (1994)
  • Chien, D., et al.: J. Pharm. Sci., 86, 1180 (1994)
  • Harrison, D., et al.: Biochemistry, 36, 16134 (1994)
  • Da Settimo, F., et al.: J. Med. Chem., 44, 316 (