L-(+)-threo-Chloramphenicol

• Catalog No.: C325025
• CAS Number: 134-90-7
• M. F.: C11H12Cl2N2O5
• M. W.: 323.12938

SYNONYMS

• IUPAC name: 2,2-dichloro-N-[(1S,2S)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• IUPAC Traditional name: amphenicol
• Synonyms: (1S,2S)-2-(2,2-Dichloroacetamido)-1-(4-nitrophenyl)-1,3-propanediol; 2,2-Dichloro-N-[(1S,2S)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide; L-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol; (+)-Chloramphenicol; Dextramycin; Dextromycetin; L-threo-Chloramphenicol; L-threo-Chloroamphenicol

DATABASE IDS

• CAS Number: 134-90-7

DETAILS

Description (English)

The S,S-stereoisomer of Chloramphenicol (C325030). Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antiric

REFERENCES

• Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948)
• Gottlieb, et al.: J. Bacteriol., 55, 409 (1948)
• Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1948)
• Price, A., et al.: J. Antibiot., 43, 118 (1948)
• Shalit, I., et al.: Drugs, 28, 281