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(S)-Cetirizine Dihydrochloride_Molecular_structure_CAS_163837-48-7)
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(S)-Cetirizine Dihydrochloride

Catalog No. C281105 Name Toronto Research Chemicals
CAS Number 163837-48-7 Website http://www.trc-canada.com
M. F. C21H25ClN2O3 Telephone +1 (416) 665-9696
M. W. 388.8878 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 164014

SYNONYMS

IUPAC name
2-(2-{4-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
IUPAC Traditional name
(2-{4-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
Synonyms
Dextrocetirizine Dihydrochloride
(+)-Cetirizine Dihydrochloride
(S)-[2-[4-[(4-Chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic Acid Dihydrochloride

DATABASE IDS

CAS Number 163837-48-7

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 189-194°C
Solubility Water
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.

REFERENCES

  • De Vos, C., et al.: Ann. Allergy, 59, 278 (1987)
  • Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987)
  • Fadel, R., et al.: Clin. Allergy, 17, 373 (1987)
  • Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)