C16-Ceramide-13C2,d2

• Catalog No.: C262902
• M. F.: C34H67NO3
• M. W.: 539.88598968

SYNONYMS

• IUPAC name: N-[(2R,3R,4E)-1,3-dihydroxy(1,2-^1^3C₂,1,1-^2H₂)octadec-4-en-2-yl]hexadecanamide
• IUPAC Traditional name: N-[(2R,3R,4E)-1,3-dihydroxy(1,2-^1^3C₂,1,1-^2H₂)octadec-4-en-2-yl]hexadecanamide
• Synonyms: D-erythro-C16-Ceramide-13C2,d2; D-erythro-N-Hexadecanoylsphingenine-13C2,d2; N-Palmitoyl 4-sphingenine-13C2,d2; D-erythro-N-Palmitoylsphingosine-13C2,d2; N-Hexadecanoyl-D-erythro-ceramide-13C2,d2; N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-hexadecanamide-13C2,d2; (2S,3R,4E)-2-N-Palmitoyloctadecasphinga-4-ene-13C2,d2; D-erythro-4-Ceramide-13C2,d2; N-Palmitoyl-D-erythro-sphingosine-13C2,d2; N-Palmitoyl-D-sphingosine-13C2,d2; N-Palmitoylsphingosinee-13C2,d2

DETAILS

Description (English)

Labelled C16-Ceramide (C262900). A predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphatase in T9 cells; induces EGF receptor phosphorylation in A-431 cells; stimulates ceramide-activated protein kinase

REFERENCES

• Shoyama, Y., et al.: J. Lipid Res., 19, 250 (1978)
• Mathias, S., et al.: Proc. Natl. Sci. USA, 88, 10009 (1978)
• Dobrowsky, R.T., et al.: J. Biol. Chem., 267, 5048 (1992)