C2 Ceramide

• Catalog No.: C262500
• CAS Number: 3102-57-6
• M. F.: C20H39NO3
• M. W.: 341.52856
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]acetamide
• IUPAC Traditional name: C2-ceramide
• Synonyms: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide; Acetyl Ceramide; N-Acetyl-D-sphingosine; N-Acetylsphingosine

DATABASE IDS

• CAS Number: 3102-57-6

PROPERTIES

• Storage Condition: -20°C Freezer
• Apperance: White Solid
• Melting Point: 87-89°C
• Solubility: Chloroform
• Solubility: Dichloromethane

DETAILS

Description (English)

A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2.

REFERENCES

• Inoue, T., et al.: J. Biol. Chem., 284, 9566 (2009)
• Kang, J., et al.: Bioorg. Med. Chem., 17, 1498 (2009)
• Rath, G., et al.: Int. J. Biochem. Cell Biol., 41, 1165 (2009)