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C2 Ceramide

Catalog No. C262500 Name Toronto Research Chemicals
CAS Number 3102-57-6 Website http://www.trc-canada.com
M. F. C20H39NO3 Telephone +1 (416) 665-9696
M. W. 341.52856 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 90871

SYNONYMS

IUPAC name
N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]acetamide
IUPAC Traditional name
C2-ceramide
Synonyms
N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide
Acetyl Ceramide
N-Acetyl-D-sphingosine
N-Acetylsphingosine

DATABASE IDS

CAS Number 3102-57-6

PROPERTIES

Storage Condition -20°C Freezer
MSDS Link Download
Certificate of Analysis Download
Apperance White Solid
Melting Point 87-89°C
Solubility Chloroform
Solubility Dichloromethane

DETAILS

Description (English)
A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2.

REFERENCES

  • Inoue, T., et al.: J. Biol. Chem., 284, 9566 (2009)
  • Kang, J., et al.: Bioorg. Med. Chem., 17, 1498 (2009)
  • Rath, G., et al.: Int. J. Biochem. Cell Biol., 41, 1165 (2009)