Cephalomannine

• Catalog No.: C258500
• CAS Number: 71610-00-9
• M. F.: C45H53NO14
• M. W.: 831.90062
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-[(2E)-2-methylbut-2-enamido]-3-phenylpropanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC Traditional name: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-[(2E)-2-methylbut-2-enamido]-3-phenylpropanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• Synonyms: (αR,βS)-α-Hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; Taxol B; NSC 318735

DATABASE IDS

• CAS Number: 71610-00-9

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 139-141°C
• Solubility: Chlorform
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Antitumor, antiproliferative.

REFERENCES

• Stenken, J., et al.: J. Pharm. Sci., 86, 958 (1997)
• Kobayashi, J., et al.: Bioorg. Med. Chem. Lett., 8, 1555 (1997)
• Andreu, J., et al.: Biochemistry, 40, 11975 (1997)
• Markman, M., et al.: J. Clin. Oncol., 24, 988 (1997)