CDDO Imidazolide

• Catalog No.: C228090
• CAS Number: 443104-02-7
• M. F.: C34H43N3O3
• M. W.: 541.72352
• Storage: Amber Vial, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (4aR,6aS,6bR,8aS,12aS,12bR,14bS)-8a-(1H-imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-2-carbonitrile
• IUPAC Traditional name: (4aR,6aS,6bR,8aS,12aS,12bR,14bS)-8a-(imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-4a,5,6,7,8,9,10,12,12a,12b-decahydropicene-2-carbonitrile
• Synonyms: CDDO-Im; 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid imidazolide; RTA 403; TP 235

DATABASE IDS

• CAS Number: 443104-02-7

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 180-192°C (dec.)
• Solubility: Chloroform
• Storage Condition: Amber Vial, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

CDDO Imidozolide (CDDO-Im) is a synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Studies show that CDDO-Im is highly active in suppressing cellular prolif

REFERENCES

• Hughes, D.T. et al.: Cancer Invest., 26, 118 (2008)
• Place, A.E. et al.: Clin. Cancer Res., 9, 2798 (2008)
• Samudio, I. et al.: J. Biol. Chem., 280, 36273 (2008)