Caspofungin Acetate

• Catalog No.: C184900
• CAS Number: 179463-17-3
• M. F.: C52H88N10O15
• M. W.: 1093.31312
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: N-[(3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-3-[(1R)-3-amino-1-hydroxypropyl]-21-[(2-aminoethyl)amino]-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,25-trihydroxy-15-[(1R)-1-hydroxyethyl]-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0^9,^1^3]heptacosan-18-yl]-10,12-dimethyltetradecanamide
• IUPAC Traditional name: caspofungin
• Synonyms: L 743872; Caspofungin Diacetate; MK 0991; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate; Cancidas; L 743873; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate

DATABASE IDS

• CAS Number: 179463-17-3

PROPERTIES

• Apperance: White Solid
• Melting Point: 204-206°C
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

An echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. An antifungal drug used in the treatment of invasive fungal infections.

REFERENCES

• Sandhu, P. et al.: Antimicrob. Agents Chemorther., 48, 1272 (2004)
• Bertsche, T. et al.: Pharamaz. Zeit., 148, 34 (2004)
• Hoang, A.: Am. J. Health-Sys. Pharm., 58, 1206 (2004)