(S)-(-)-Carbidopa

• Catalog No.: C175985
• CAS Number: 28860-95-9
• M. F.: C10H14N2O4
• M. W.: 226.22916

SYNONYMS

• IUPAC name: (2R)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
• IUPAC Traditional name: (2R)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
• Synonyms: Hydrazino-α-methyldopa; L-α-Methyl-β-(3,4-dihydroxyphenyl)-α-hydrazinopropionic Acid; L-α-Methyldopahydrazine; HMD; Carbidopa; (αS)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic Acid; (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinamic Acid; (S)-Carbidopa; 1-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic Acid; L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic Acid; L-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic Acid; Lodosin; Lodosyn; α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic Acid; α-Methyldopahydrazine; MK 486; N-Aminomethyldopa

DATABASE IDS

• CAS Number: 28860-95-9

DETAILS

Description (English)

(S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA (D533751) for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and s

REFERENCES

• Henry, G.M. et al.: Psychosom. Med., 38, 95 (1976)
• Leguire, L.E. et al.: Invest. Ophthalmol. Vis. Sci. 34, 3090 (1976)
• Deleu, D. et al.: Naun. Schmied. Arch. Pharmacol. 348: 576 (1976)