Capecitabine Benzoate (mixture of 2'(3')-benzoate isomers)

• Catalog No.: C175670
• M. F.: C44H52F2N6O14
• M. W.: 926.9122864

SYNONYMS

• IUPAC name: (2R,3R,4R,5R)-2-(5-fluoro-2-oxo-4-{[(pentyloxy)carbonyl]amino}-1,2-dihydropyrimidin-1-yl)-4-hydroxy-5-methyloxolan-3-yl benzoate (2R,3S,4R,5R)-5-(5-fluoro-2-oxo-4-{[(pentyloxy)carbonyl]amino}-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-methyloxolan-3-yl benzoate
• IUPAC Traditional name: (2R,3R,4R,5R)-2-(5-fluoro-2-oxo-4-{[(pentyloxy)carbonyl]amino}pyrimidin-1-yl)-4-hydroxy-5-methyloxolan-3-yl benzoate (2R,3S,4R,5R)-5-(5-fluoro-2-oxo-4-{[(pentyloxy)carbonyl]amino}pyrimidin-1-yl)-4-hydroxy-2-methyloxolan-3-yl benzoate
• Synonyms: 5’-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine Benozate

PROPERTIES

• Apperance: White Crystal
• Solubility: Dichloromethane

DETAILS

Description (English)

Protected Capecitabine (C175650). An antineoplastic agent. A prodrug of Doxifluridine (D556750).

REFERENCES

• Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009)
• Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009)
• Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009)
• Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009)