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Canrenone

Catalog No. C175610 Name Toronto Research Chemicals
CAS Number 976-71-6 Website http://www.trc-canada.com
M. F. C22H28O3 Telephone +1 (416) 665-9696
M. W. 340.45592 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 163597

SYNONYMS

IUPAC name
(1'S,2R,2'R,10'R,11'S,15'S)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadecane]-6',8'-diene-5,5'-dione
IUPAC Traditional name
canrenone
Synonyms
(17α)-17-Hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic Acid γ-Lactone
Phanurane
17α-2-Carboxyethyl-17β-hydroxyandrosta-4,6-dien-3-one Lactone

DATABASE IDS

CAS Number 976-71-6

PROPERTIES

Certificate of Analysis Download
Apperance Pale yellow to pale Green Solid
Melting Point 158-160°C
Solubility Acetone
Solubility Chloroform
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Aldosterone antagonist. Diuretic.

REFERENCES

  • Sadee, W., et al.: J. Pharmacol. Exp. Ther., 185, 686 (1973)
  • Pitt, B., et al.: Circulation, 108, 1831 (1973)
  • Silvestre, J., et al.: J. Biol. Chem., 273, 4883 (1973)
  • Struthers, A., et al.: Heart, 92, 1728 (1973)