Candesartan cilexetil

• Catalog No.: C175580
• CAS Number: 145040-37-5
• M. F.: C33H34N6O6
• M. W.: 610.65966
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-1,3-benzodiazole-7-carboxylate
• IUPAC Traditional name: 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-3-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-benzodiazole-4-carboxylate
• Synonyms: TCV 116; Blopress; 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl Ester; Atacand

DATABASE IDS

• CAS Number: 145040-37-5

PROPERTIES

• Apperance: White Solid
• Melting Point: 168-170°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.

REFERENCES

• Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993)
• Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)