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ent-Calindol Hydrochloride

Catalog No. C148705 Name Toronto Research Chemicals
CAS Number 728930-30-1 Website http://www.trc-canada.com
M. F. C21H21ClN2 Telephone +1 (416) 665-9696
M. W. 336.85784 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 163554

SYNONYMS

IUPAC name
(1H-indol-2-ylmethyl)[(1S)-1-(naphthalen-1-yl)ethyl]amine hydrochloride
IUPAC Traditional name
(1H-indol-2-ylmethyl)[(1S)-1-(naphthalen-1-yl)ethyl]amine hydrochloride
Synonyms
N-[(1S)-1-(1-Naphthalenyl)ethyl]-1H-indole-2-methanamine Hydrochloride
(S)-2-[[[1-(1-Naphthyl)ethyl]amino]methyl]-1H-indole Hydrochloride

DATABASE IDS

CAS Number 728930-30-1

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point >196°C (dec.)
Solubility DMF
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
A new calcimimetic acting at the calcium sensing receptor; a positive allosteric modulator of the human Ca2+ receptor, activates an extracellular ligand-binding domain-deleted Rhodopsin-like seven-transmembrane structure in the absence of Ca2+.

REFERENCES

  • Fawzi, A., et al.: Biochemistry, 29, 3804 (1990)
  • Han, G., et al.: J. Biol. Chem., 274, 10008 (1990)
  • Palczewski, K., et al.: Science, 289, 739 (1990)
  • Nemeth, E., et al.: J. Pharmacol. Exp. Ther., 299, 323 (1990)
  • Kew, J., et al.: Pharmacol. Ther., 104,