(5E)-Calcipotriene

• Catalog No.: C144210
• CAS Number: 113082-99-8
• M. F.: C27H40O3
• M. W.: 412.6047

SYNONYMS

• IUPAC name: (1R,3S,5E)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
• IUPAC Traditional name: (1R,3S,5E)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-hexahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
• Synonyms: 5,6-trans-Calcipotriol; PRI 2205; (1S,3S,5E)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol; (1α,3β,5E,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol

DATABASE IDS

• CAS Number: 113082-99-8

DETAILS

Description (English)

The trans-isomeric impurity of Calcipotriene (C144200) and a vitamin D3 analogue with antitumor effects.

REFERENCES

• Wietrzyk, J. et al.: Anti-Cancer Drugs, 18, 447 (2007)
• Wietrzyk, J. et al.: Anticancer Res., 27, 3387 (2007)
• Filip, B. et al.: J. Ster. Biochem. Mol. Biol., 121, 399 (2007)