Calcipotriene-d4

• Catalog No.: C144202
• M. F.: C27H40O3
• M. W.: 412.6047

SYNONYMS

• IUPAC name: (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-5-[(2,2,3,3-^2H₄)cyclopropyl]-5-hydroxypent-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
• IUPAC Traditional name: (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-5-[(2,2,3,3-^2H₄)cyclopropyl]-5-hydroxypent-3-en-2-yl]-7a-methyl-hexahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
• Synonyms: Daivonex-d4; Calciptriol-d4; MC-903-d4; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-(Cyclopropyl-d4)-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol; Dovonex-d4; Psorcutan-d4

DETAILS

Description (English)

A labelled antipsoriatic. A vitamin D3 analogue with low calcemic activity.

REFERENCES

• Binderup, L. and Bramm, E.: Biochem. Pharmacol., 37, 889 (1988)
• Valaja, T., et al.: Biochem. Pharmacol., 40, 1827 (1988)
• Ashcroft, D.M., et al.: Brit Med. J., 320, 963 (1988)
• Ghoreishi, M., et al.: J. Immunol., 182, 6071 (1988)
• Sato, T., et al.: J. Me