Calcipotriene

• Catalog No.: C144200
• CAS Number: 112965-21-6
• M. F.: C27H40O3
• M. W.: 412.6047
• Storage: Amber Vial, -20°C Freezer

SYNONYMS

• IUPAC name: (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
• IUPAC Traditional name: calcipotriol
• Synonyms: Calciptriol, MC-903, Daivonex, Dovonex, Psorcutan; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol

DATABASE IDS

• CAS Number: 112965-21-6

PROPERTIES

• Apperance: White Solid
• Melting Point: 156-162°C
• Solubility: Chloroform
• Storage Condition: Amber Vial, -20°C Freezer

DETAILS

Description (English)

An antipsoriatic. A vitamin D3 analogue with low calcemic activity.

REFERENCES

• Binderup, L. and Bramm, E.: Biochem. Pharmacol., 37, 889 (1988)
• Valaja, T., et al.: Biochem. Pharmacol., 40, 1827 (1988)
• Ashcroft, D.M., et al.: Brit Med. J., 320, 963 (1988)
• Ghoreishi, M., et al.: J. Immunol., 182, 6071 (1988)
• Sato, T., et al.: J. Me