21-O-tert-Butyldimethylsilyl Prednisone

• Catalog No.: B691830
• M. F.: C27H40O5Si
• M. W.: 472.689

SYNONYMS

• IUPAC name: (1S,2R,10S,11S,14R,15S)-14-{2-[(tert-butyldimethylsilyl)oxy]acetyl}-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-5,17-dione
• IUPAC Traditional name: (1S,2R,10S,11S,14R,15S)-14-{2-[(tert-butyldimethylsilyl)oxy]acetyl}-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-5,17-dione

PROPERTIES

• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Methanol

DETAILS

Description (English)

Protected Prednisone (P703780). Adrenocortical steroid. Glucocorticoid, antiinflammatory.

REFERENCES

• Wingerchuk, D., et al.: Neurology, 66, 1485 (2004)
• Fliri, A.F., et al.: J. Med. Chem., 52, 8038 ((2004)
• Lennon, V., et al.: Lancet, 364, 2106 (2004)