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1-Butyl-3-(1,1-dioxido-2H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinone_Molecular_structure_CAS_303776-83-2)
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1-Butyl-3-(1,1-dioxido-2H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinone

Catalog No. B691765 Name Toronto Research Chemicals
CAS Number 303776-83-2 Website http://www.trc-canada.com
M. F. C20H19N3O4S Telephone +1 (416) 665-9696
M. W. 397.44756 Fax +1 (416) 665-4439
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Storage Chembase ID: 163424

SYNONYMS

IUPAC name
3-(1-butyl-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-4H-1λ6,2,4-benzothiadiazine-1,1-dione
IUPAC Traditional name
3-(1-butyl-4-hydroxy-2-oxoquinolin-3-yl)-4H-1λ6,2,4-benzothiadiazine-1,1-dione

DATABASE IDS

CAS Number 303776-83-2

PROPERTIES

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DETAILS

Description (English)
Heterocyclic inhibitor of the RNA-dependent RNA polymerase enzyme transcribed by the Hepatitis C virus.

REFERENCES

  • Mashino, T., et al.: Bioorg. Med. Chem. Lett., 15, 1107 (2005)
  • Liu, Y., et al.: Biochem., 45, 11312 (2005)
  • Tedesco, R., et al.: J. Med. Chem., 49, 971 (2005)