2'-O-(tert-Butyldimethylsilyl) Paclitaxel

• Catalog No.: B691630
• CAS Number: 114655-02-6
• M. F.: C53H65NO14Si
• M. W.: 968.167

SYNONYMS

• IUPAC name: (1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-2-[(tert-butyldimethylsilyl)oxy]-3-phenyl-3-(phenylformamido)propanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC Traditional name: (1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-2-[(tert-butyldimethylsilyl)oxy]-3-phenyl-3-(phenylformamido)propanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• Synonyms: 2'-O-(tert-Butyldimethylsilyl)taxol

DATABASE IDS

• CAS Number: 114655-02-6

PROPERTIES

• Apperance: White Solid
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol

DETAILS

Description (English)

Paclitaxel derivative as antitumor agent.

REFERENCES

• Magri, N.F., et al.: J. Nat. Prod. 51, 298 (1988)
• Kingston, D., et al.: Pharmac. Ther., 52, 1 (1988)
• Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995)